⊟Summary[edit | edit source]

PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
locus tag: SA_RS05450 [old locus tag: SA0962 ]
pan locus tag^?: SAUPAN003340000
symbol: SA_RS05450
pan gene symbol^?: ftsW
• synonym:
• product: cell division protein FtsW

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS05450 [old locus tag: SA0962 ]
• symbol: SA_RS05450
• product: cell division protein FtsW
• replicon: chromosome
• strand: +
• coordinates: 1089462..1090688
• length: 1227
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (1089462..1090688) NCBI
• BioCyc: SA_RS05450 BioCyc
• MicrobesOnline: see SA0962

⊟Phenotype

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⊟DNA sequence

• 1
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  ATGAAGAATTTTAGAAGTATTTTACGGTATATTGGTAAAACCTCAAAGTTTATTGATTAT
  CCGTTATTAGTTACATATATTGTATTGAGTTTAATTGGATTAGTGATGGTATATAGTGCA
  AGTATGGTTCCAGCAACTAAAGGCACATTGACTGGTGGTATCGATGTTCCAGGAACGTAT
  TTTTACAACCGACAATTAGCATATGTCATAATGAGTTTTATAATTGTATTTTTTATTGCA
  TTTTTAATGAATGTTAAATTACTGAGTAATATTAAAGTGCAAAAAGGTATGATTATAACT
  ATCGTCTCACTATTATTACTGACGTTAGTAATAGGTAAAGATATTAATGGTTCTAAAAGT
  TGGATAAACTTAGGATTTATGAATTTACAGGCATCTGAGTTATTAAAAATTGCAATCATA
  TTATATATCCCATTTATGATCAGTAAAAAAATGCCTAGAGTATTAAGTAAACCAAAATTA
  ATTTTAAGTCCTATTGTATTAGCATTAGGTTGTACGTTTTTAGTTTTCTTACAAAAAGAC
  GTAGGGCAAACATTACTAATATTAATTATTTTAGTTGCGATTATTTTTTATTCAGGAATT
  GGGGTAAACAAAGTCCTAAGATTTGGTATACCAGCAGTGCTAGGATTCTTAGTAGTATTT
  GTCATTGCATTAATGGCTGGTTGGTTACCAAGCTATTTAACTGCCAGATTTAGTACGCTA
  ACAGATCCATTCCAATTCGAATCAGGAACTGGATACCATATTTCCAATTCATTGCTTGCG
  ATAGGTAACGGTGGCGTATTTGGAAAAGGATTAGGAAATAGTGCAATGAAATTGGGCTAT
  TTACCAGAACCACATACAGATTTTATTTTTGCAATTATTTGCGAAGAATTAGGTTTAATC
  GGAGGATTGCTAGTTATTACTTTAGAGTTCTTTATTGTATATCGTGCCTTCCAGTTTGCA
  AATAAAACATCATCATATTTTTATAAACTTGTGTGTGTTGGGATTGCCACATACTTTGGA
  AGTCAAACGTTTGTAAACATTGGCGGTATTTCGGCAACAATTCCATTAACTGGTGTGCCA
  TTGCCATTTATCAGCTTTGGTGGATCATCAATGATTAGTTTAAGTATTGCTATGGGATTA
  CTTCTGATTGTAGGTAAACAAATCAAAGTAGACCAGCAACGAAAGAAACAACAACAAAAA
  GTTGATATAAGAAGACAATTTAATTAA
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  1227
  

⊟Protein

⊟General

• locus tag: SA_RS05450 [old locus tag: SA0962 ]
• symbol: SA_RS05450
• description: cell division protein FtsW
• length: 408
• theoretical pI: 10.3601
• theoretical MW: 44881.8
• GRAVY: 0.8125

⊟Function

• TIGRFAM:
  Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan cell division protein FtsW (TIGR02614; HMM-score: 292.7)
  Cellular processes Cellular processes Cell division cell division protein FtsW (TIGR02614; HMM-score: 292.7)
  Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan rod shape-determining protein RodA (TIGR02210; HMM-score: 268.2)
  Cellular processes Cellular processes Cell division rod shape-determining protein RodA (TIGR02210; HMM-score: 268.2)
  Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan stage V sporulation protein E (TIGR02615; HMM-score: 234.3)
  Cellular processes Cellular processes Sporulation and germination stage V sporulation protein E (TIGR02615; HMM-score: 234.3)
• TheSEED: see SA0962
• PFAM:
  Membrane_trans (CL0142) FTSW_RODA_SPOVE; Cell cycle protein (PF01098; HMM-score: 291.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞⊞PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 10
• ⊞⊞DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.9995
  • Cell wall & surface Score: 0
  • Extracellular Score: 0.0005
• LocateP:
• ⊞⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.340562
  • TAT(Tat/SPI): 0.003618
  • LIPO(Sec/SPII): 0.013271
• predicted transmembrane helices (TMHMM): 10

⊟Accession numbers

• GI: 446710594 NCBI
• RefSeq: WP_000787940 NCBI
• UniProt: see SA0962

⊟Protein sequence

• MKNFRSILRYIGKTSKFIDYPLLVTYIVLSLIGLVMVYSASMVPATKGTLTGGIDVPGTYFYNRQLAYVIMSFIIVFFIAFLMNVKLLSNIKVQKGMIITIVSLLLLTLVIGKDINGSKSWINLGFMNLQASELLKIAIILYIPFMISKKMPRVLSKPKLILSPIVLALGCTFLVFLQKDVGQTLLILIILVAIIFYSGIGVNKVLRFGIPAVLGFLVVFVIALMAGWLPSYLTARFSTLTDPFQFESGTGYHISNSLLAIGNGGVFGKGLGNSAMKLGYLPEPHTDFIFAIICEELGLIGGLLVITLEFFIVYRAFQFANKTSSYFYKLVCVGIATYFGSQTFVNIGGISATIPLTGVPLPFISFGGSSMISLSIAMGLLLIVGKQIKVDQQRKKQQQKVDIRRQFN

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications