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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1839 [new locus tag: SA_RS10550 ]
  • pan locus tag?: SAUPAN005268000
  • symbol: SA1839
  • pan gene symbol?: sdrH
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1839 [new locus tag: SA_RS10550 ]
  • symbol: SA1839
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2075260..2076507
  • length: 1248
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGTCATATCATTGGTTTAAGAAAATGTTACTTTCAACAAGTATTTTAATTTTAAGTAGT
    AGTAGTTTAGGGCTTGCAACGCACACAGTTGAAGCAAAGGATAACTTAAATGGAGAAAAA
    CCAACTACTAATTTGAATCATAATATAACTTCACCATCAGTAAATAGTGAAATGAATAAT
    AATGAGACTGGGACACCTCACGAATCAAATCAAACGGGTAATGAAGGAACAGGTTCGAAT
    AGTCGTGATGCTAATCCTGATTCGAATAATGTGAAGCCAGACTCAAACAACCAAAACCCA
    AGTACAGATTCAAAACCAGACCCAAATAACCAAAACCCAAGTCCGAATCCAAAACCAGAT
    CCAGATAACCCGAAACCAAAACCAGACCCAGATAAACCAAAGCCAAATCTGGATCCAAAA
    CCAGATCCAGATAACCCGAAACCAAAACCAGATCCAAAACCAGACCCAGATAAACCAAAG
    CCAAATCCGGATCCAAAACCAGATCCAGATAAACCAAAGCCAAATCCGAATCCAAAACCA
    GACCCTAATAAGCCAAATCCTAACCCGTCACCAGATCCCGATCAACCTGGGGATTCAAAT
    CATTCTGGTGGCTCGAAAAATGGGGGAACATGGAACCCAAATGCTTCAGATGGATCTAAT
    CAAGGTCAATGGCAACCAAATGGGAATCAAGGAAACTCACAAAATCCTACTGGTAATGAT
    TTTGTATCCCAACGATTTTTAGCCTTGGCAAATGGGGCTTACAAGTATAATCCGTATATT
    TTAAATCAAATTAATAAGTTGGGCAAAGATTATGGAGAAGTTACTGATGAAGACATTTAT
    AATATTATTCGAAAACAAAATTTCAGCGGAAATGCATATTTAAATGGATTACAACAGCAA
    TCGAATTACTTTAGATTCCAATATTTCAATCCATTGAAATCAGAAAGGTACTATCGTAAT
    TTAGATGAACAAGTACTCGCATTAATTACTGGTGAAATTGGATCAATGCCAGATTTGAAA
    AAGCCCGAAGATAAGCCGGATTCAAAACAACGCTCATTTGAACCGCATGAAAAAGACGAT
    TTTACAGTAGTTAAAAAACAAGAAGATAATAAGAAAAGTGCGTCAACTGCATATAGTAAA
    AGTTGGCTAGCAATTGTATGTTCTATGATGGTGGTATTTTCAATCATGCTATTCTTATTT
    GTAAAGCGAAATAAAAAGAAAAATAAAAACGAATCACAGCGACGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1248

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1839 [new locus tag: SA_RS10550 ]
  • symbol: SA1839
  • description: hypothetical protein
  • length: 415
  • theoretical pI: 8.72247
  • theoretical MW: 46222.4
  • GRAVY: -1.38096

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Membrane anchored protein
  • ⊞PFAM:
    no clan defined PFF1_TM; Vacuolar membrane protease, transmembrane domain (PF22251; HMM-score: 15.9)
    Orf78; Orf78 (ac78) (PF06024; HMM-score: 14.1)
    and 4 more
    COX2-transmemb; Cytochrome C oxidase subunit II, transmembrane (PF09125; HMM-score: 11.8)
    NEDD4_Bsd2; NEDD4/Bsd2 (PF10176; HMM-score: 10)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 7.6)
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 6.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helices: 2
  • ⊞DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.215
    • Cell wall & surface Score: 0.592
    • Extracellular Score: 0.1927
  • ⊞LocateP: C-terminally anchored (with CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: -2
    • Predicted Cleavage Site: HTVEAKDN
  • ⊞SignalP: Signal peptide SP(Sec/SPI) length 32 aa
    • SP(Sec/SPI): 0.990235
    • TAT(Tat/SPI): 0.006169
    • LIPO(Sec/SPII): 0.002709
    • Cleavage Site: CS pos: 32-33. VEA-KD. Pr: 0.9595
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPDKPKPNLDPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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