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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS13150 [old locus tag: SA2293 ]
  • pan locus tag?: SAUPAN006130000
  • symbol: SA_RS13150
  • pan gene symbol?: gntP
  • synonym:
  • product: gluconate permease

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS13150 [old locus tag: SA2293 ]
  • symbol: SA_RS13150
  • product: gluconate permease
  • replicon: chromosome
  • strand: -
  • coordinates: 2575474..2576832
  • length: 1359
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (2575474..2576832) NCBI
  • BioCyc: SA_RS13150 BioCyc
  • MicrobesOnline: see SA2293

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGTTTAACGAAATATGGCCGTTAATCAGTGTTGTTTTAGGTATCGTTATTTTATTAGTA
    TTAATTATTGGGTTTAAATTAAATACATTTATTTCATTAATTATCACATCGATGATTACA
    GCGTTAATGCTAGGTATACCATTGACTAAAATTATGGAGACGATTGAGAAAGGGATGGGC
    AGTACGCTCGGCCACATTGCACTAATATTCGGTTTAGGTGCCATACTTGGGAAATTACTT
    GCTGATGGTGGTGGTGCAACTCGAATTGCAGACACGTTGATTCAAAAATTTGGTCAAAAA
    CATGTACAATGGGCAATGCTTGTTGCAGCATTTATCGTCGGTATTGCATTGTTCTTTGAA
    GTAGGTTTAGTCTTACTGATTCCATTAGTATTTACAGTAGCAAAACGCGCAAATGTTTCA
    GTGTTAAAACTAGGACTACCTATGGTAACAGCTTTATCTGTGACACATGGCTTTTTACCA
    CCACATCCAGGACCGGTAGTCATCGCAAAAGAATTAAAGGCAAATGTTGGAGATGTATTA
    CTGTACGGTATGATTATTGCCATTCCAGTTACACTCATTGCAGGACCTATATTTAACAAA
    GTTGCACAAAAAATGATTCCGTCTGCGTATACACGAGAAGGCGATATTTCAGCGTTAGGT
    GCACAAAAAGAATTTACGGATCAAGAGATGCCAGGATTTGGTATGAGTTTATTAACTGCA
    ACATTACCAGTCATATTAATGTTAGTGTCTACGATAACGCAACTTGTAACTGGGCACGAC
    AAACCTACAAATCTATTTGAATCTATCATTTATATGATAGGAACAGCAGGGACAGCCATG
    CTAATAGCAGTATTATTTGCAATCGTTACGATGGGATTAATGAGAAAACGTAAGATGAAT
    CATATTATGGAATCAGTGACGAATGCGATTTATCCAATCGGAATGATGTTATTGATTATT
    GGCGGTGGCGGTACATTTAAACAAGTATTAATTGACGGTGGTGTCGGAAATACAATTGCT
    AAAATGTTTGAAGGTACAGAGATGTCTCCAATTTTACTAGCATGGATTGTTGCAGCTGTG
    CTACGTATCGCATTAGGTTCGGCTACAGTAGCTGCGATTTCAACTACAGGTATTGTCTTA
    CCATTATTACAATCATCAGATGTAAATGTTGCATTAGTTGTACTTGCGATAGGTGCAGGT
    AGTGTGATTTTGTCTCATGTAAATGACGCAGGATTTTGGATGTTTAAAGAATATTTTGGT
    TTAACTGTAAAAGAAACATTCTTAACATGGTCATTATTAGAAACGATTATTTCCGTTTCA
    GGTATCATCTTCATTCTATTCATCAGCTTATTTGTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1359

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS13150 [old locus tag: SA2293 ]
  • symbol: SA_RS13150
  • description: gluconate permease
  • length: 452
  • theoretical pI: 9.2587
  • theoretical MW: 48102.9
  • GRAVY: 1.02942

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids transporter, gluconate:H+ symporter (GntP) family (TIGR00791; HMM-score: 600.4)
  • TheSEED: see SA2293
  • PFAM:
    IT (CL0182) GntP_permease; GntP family permease (PF02447; HMM-score: 570.6)
    and 4 more
    CitMHS; Citrate transporter (PF03600; HMM-score: 72.3)
    Na_H_antiport_2; Na+-H+ antiporter family (PF13726; HMM-score: 16.9)
    no clan defined Tim17; Tim17/Tim22/Tim23/Pmp24 family (PF02466; HMM-score: 10.6)
    IT (CL0182) DctM; Tripartite ATP-independent periplasmic transporter, DctM component (PF06808; HMM-score: 7.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001856
    • TAT(Tat/SPI): 0.000172
    • LIPO(Sec/SPII): 0.001043
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator: CcpA, GntR see SA2293

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]