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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12280 [old locus tag: SA2138 ]
  • pan locus tag?: SAUPAN005847000
  • symbol: SA_RS12280
  • pan gene symbol?:
  • synonym:
  • product: 3-hydroxyacyl-CoA dehydrogenase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12280 [old locus tag: SA2138 ]
  • symbol: SA_RS12280
  • product: 3-hydroxyacyl-CoA dehydrogenase
  • replicon: chromosome
  • strand: +
  • coordinates: 2403590..2404081
  • length: 492
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (2403590..2404081) NCBI
  • BioCyc: G1G21-2491 BioCyc
  • MicrobesOnline: see SA2138

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGGTTATTATCAAACAACTTTTTACACATACTCAAACCGTAACATCTGAATTCATTGAC
    CATAACAATCATATGCATGATGCAAATTATAATATCATTTTTAGTGACGTCGTGAATCGT
    TTTAATTACAGCCACGGTCTTTCTTTAAAAGAACGCGAAAATTTAGCATATACACTATTT
    ACACTAGAAGAACATACGACATACCTCTCAGAATTGTCTCTTGGCGATGTATTTACTGTT
    ACTTTATATATTTATGATTACGATTATAAGCGGTTGCATTTATTTTTAACATTAACTAAA
    GAAGATGGTACACTAGCATCAACAAATGAAGTAATGATGATGGGAATTAATCAGCACACA
    CGTCGTTCTGATGCTTTTCCTGAATCATTCTCAACACAAATAGCACACTATTATAAAAAT
    CAACCAACTATCACTTGGCCTGAACAATTAGGACATAAAATAGCAATTCCACACAAAGGA
    GCATTAAAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    492

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS12280 [old locus tag: SA2138 ]
  • symbol: SA_RS12280
  • description: 3-hydroxyacyl-CoA dehydrogenase
  • length: 163
  • theoretical pI: 6.58504
  • theoretical MW: 19034.4
  • GRAVY: -0.370552

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General acyl-CoA thioester hydrolase, YbgC/YbaW family (TIGR00051; HMM-score: 17.2)
    and 1 more
    tol-pal system-associated acyl-CoA thioesterase (TIGR02799; EC 3.1.2.-; HMM-score: 13.7)
  • TheSEED: see SA2138
  • PFAM:
    HotDog (CL0050) 4HBT_2; Thioesterase-like superfamily (PF13279; HMM-score: 57.2)
    and 2 more
    4HBT; Thioesterase superfamily (PF03061; HMM-score: 15.4)
    no clan defined Tmpp129; Putative transmembrane protein precursor (PF10272; HMM-score: 9.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002901
    • TAT(Tat/SPI): 0.000141
    • LIPO(Sec/SPII): 0.000476
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MVIIKQLFTHTQTVTSEFIDHNNHMHDANYNIIFSDVVNRFNYSHGLSLKERENLAYTLFTLEEHTTYLSELSLGDVFTVTLYIYDYDYKRLHLFLTLTKEDGTLASTNEVMMMGINQHTRRSDAFPESFSTQIAHYYKNQPTITWPEQLGHKIAIPHKGALK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]