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m (Text replacement - "gene Genbank" to "gene RefSeq")
m (Text replacement - "* <aureodatabase>protein Genbank</aureodatabase> " to "")
 
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__TOC__
<protect>
<protect>
<aureodatabase>NCBI date</aureodatabase>
<aureodatabase>annotation</aureodatabase>


=Summary=
=Summary=


* <aureodatabase>organism</aureodatabase>
*<aureodatabase>organism</aureodatabase>
* <aureodatabase>locus</aureodatabase>
*<aureodatabase>locus</aureodatabase>
* <aureodatabase>pan locus</aureodatabase>
*<aureodatabase>pan locus</aureodatabase>
* <aureodatabase>gene symbol</aureodatabase>
*<aureodatabase>gene symbol</aureodatabase>
* <aureodatabase>pan gene symbol</aureodatabase>
*<aureodatabase>pan gene symbol</aureodatabase>
* <aureodatabase>gene synonyms</aureodatabase>
*<aureodatabase>gene synonyms</aureodatabase>
* <aureodatabase>product</aureodatabase>
*<aureodatabase>product</aureodatabase>
</protect>
</protect>


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==General==
==General==


* <aureodatabase>gene type</aureodatabase>
*<aureodatabase>gene type</aureodatabase>
* <aureodatabase>locus</aureodatabase>
*<aureodatabase>locus</aureodatabase>
* <aureodatabase>gene symbol</aureodatabase>
*<aureodatabase>gene symbol</aureodatabase>
* <aureodatabase>product</aureodatabase>
*<aureodatabase>product</aureodatabase>
* <aureodatabase>gene replicon</aureodatabase>
*<aureodatabase>gene replicon</aureodatabase>
* <aureodatabase>strand</aureodatabase>
*<aureodatabase>strand</aureodatabase>
* <aureodatabase>gene coordinates</aureodatabase>
*<aureodatabase>gene coordinates</aureodatabase>
* <aureodatabase>gene length</aureodatabase>
*<aureodatabase>gene length</aureodatabase>
* <aureodatabase>essential</aureodatabase>
*<aureodatabase>essential</aureodatabase>
*<aureodatabase>gene comment</aureodatabase>
</protect>
</protect>


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==Accession numbers==
==Accession numbers==


* <aureodatabase>gene GI</aureodatabase>
*<aureodatabase>gene location</aureodatabase>
* <aureodatabase>gene RefSeq</aureodatabase>
*<aureodatabase>gene BioCyc</aureodatabase>
*<aureodatabase>gene MicrobesOnline</aureodatabase>
</protect>
</protect>
   
   
<protect>  
<protect>
==Phenotype==
==Phenotype==
</protect>
</protect>
* Share your knowledge and add information here. [<span class="plainlinks">[http://www.protecs.uni-greifswald.de/aureowiki/index.php?title={{PAGENAMEE}}&action=edit&section=6 edit]</span>]
Share your knowledge and add information here. [<span class="plainlinks">[//aureowiki.med.uni-greifswald.de/index.php?title={{PAGENAMEE}}&veaction=edit&section=6 edit]</span>]


<protect>
<protect>
==DNA sequence==
==DNA sequence==


* <aureodatabase>gene sequence</aureodatabase>
*<aureodatabase>gene sequence</aureodatabase>
</protect>
</protect>


<protect>
<protect>
<aureodatabase>RNA regulated operons</aureodatabase>
</protect>


<protect>
=Protein=
=Protein=
<aureodatabase>protein 3D view</aureodatabase>
<aureodatabase>protein 3D view</aureodatabase>
==General==
==General==


* <aureodatabase>locus</aureodatabase>
*<aureodatabase>locus</aureodatabase>
* <aureodatabase>protein symbol</aureodatabase>
*<aureodatabase>protein symbol</aureodatabase>
* <aureodatabase>protein description</aureodatabase>
*<aureodatabase>protein description</aureodatabase>
* <aureodatabase>protein length</aureodatabase>
*<aureodatabase>protein length</aureodatabase>
* <aureodatabase>theoretical pI</aureodatabase>
*<aureodatabase>theoretical pI</aureodatabase>
* <aureodatabase>theoretical MW</aureodatabase>
*<aureodatabase>theoretical MW</aureodatabase>
* <aureodatabase>GRAVY</aureodatabase>
*<aureodatabase>GRAVY</aureodatabase>
</protect>
</protect>


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==Function==
==Function==


* <aureodatabase>protein reaction</aureodatabase>
*<aureodatabase>protein reaction</aureodatabase>
* <aureodatabase>protein TIGRFAM</aureodatabase>
*<aureodatabase>protein TIGRFAM</aureodatabase>
* <aureodatabase>protein TheSeed</aureodatabase>
*<aureodatabase>protein TheSeed</aureodatabase>
* <aureodatabase>protein PFAM</aureodatabase>
*<aureodatabase>protein PFAM</aureodatabase>
</protect>
</protect>


<protect>
<protect>
==Structure, modifications & interactions==
==Structure, modifications & cofactors==


* <aureodatabase>protein domains</aureodatabase>
*<aureodatabase>protein domains</aureodatabase>
* <aureodatabase>protein modifications</aureodatabase>
*<aureodatabase>protein modifications</aureodatabase>
* <aureodatabase>protein cofactors</aureodatabase>
*<aureodatabase>protein cofactors</aureodatabase>
* <aureodatabase>protein effectors</aureodatabase>
*<aureodatabase>protein effectors</aureodatabase>
* <aureodatabase>protein partners</aureodatabase>
*<aureodatabase>protein regulated operons</aureodatabase>
</protect>
</protect>


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==Localization==
==Localization==


* <aureodatabase>protein Psortb</aureodatabase>
*<aureodatabase>protein Psortb</aureodatabase>
* <aureodatabase>protein LocateP</aureodatabase>
*<aureodatabase>protein LocateP</aureodatabase>
* <aureodatabase>protein SignalP</aureodatabase>
*<aureodatabase>protein SignalP</aureodatabase>
* <aureodatabase>protein TMHMM</aureodatabase>
*<aureodatabase>protein TMHMM</aureodatabase>
</protect>
</protect>


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==Accession numbers==
==Accession numbers==


* <aureodatabase>protein GI</aureodatabase>
*<aureodatabase>protein GI</aureodatabase>
* <aureodatabase>protein UniProt</aureodatabase>
*<aureodatabase>protein RefSeq</aureodatabase>
* <aureodatabase>protein Genbank</aureodatabase>
*<aureodatabase>protein UniProt</aureodatabase>
* <aureodatabase>protein RefSeq</aureodatabase>
</protect>
</protect>


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==Protein sequence==
==Protein sequence==


* <aureodatabase>protein sequence</aureodatabase>
*<aureodatabase>protein sequence</aureodatabase>
</protect>
</protect>


<protect>
<protect>
==Peptides==
==Experimental data==


* <aureodatabase>protein validated peptides</aureodatabase>
*<aureodatabase>protein validated peptides</aureodatabase>
*<aureodatabase>protein validated localization</aureodatabase>
*<aureodatabase>protein validated quantitative data</aureodatabase>
*<aureodatabase>protein partners</aureodatabase>
</protect>
</protect>


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==Operon==
==Operon==


* <aureodatabase>operons</aureodatabase>
*<aureodatabase>operons</aureodatabase>
</protect>
</protect>


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==Regulation==
==Regulation==


* <aureodatabase>sigma factors</aureodatabase>
*<aureodatabase>regulators</aureodatabase>
* <aureodatabase>regulators</aureodatabase>
</protect>
</protect>


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==Transcription pattern==
==Transcription pattern==


* <aureodatabase>expression browser</aureodatabase>
*<aureodatabase>expression browser</aureodatabase>
</protect>
</protect>


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==Protein synthesis (provided by Aureolib)==
==Protein synthesis (provided by Aureolib)==


* <aureodatabase>protein synthesis Aureolib</aureodatabase>
*<aureodatabase>protein synthesis Aureolib</aureodatabase>
</protect>
</protect>


<protect>
<protect>
==Stability==
==Protein stability==


* <aureodatabase>protein half-life</aureodatabase>
*<aureodatabase>protein half-life</aureodatabase>
</protect>
</protect>


Latest revision as of 13:32, 11 March 2016

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS10640 [old locus tag: SA1853 ]
  • pan locus tag?: SAUPAN005296000
  • symbol: SA_RS10640
  • pan gene symbol?: —
  • synonym:
  • product: DNA mismatch repair protein MutS

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS10640 [old locus tag: SA1853 ]
  • symbol: SA_RS10640
  • product: DNA mismatch repair protein MutS
  • replicon: chromosome
  • strand: +
  • coordinates: 2092597..2094207
  • length: 1611
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2092597..2094207) NCBI
  • BioCyc: SA_RS10640 BioCyc
  • MicrobesOnline: see SA1853

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAGCACAAATCAAACATTTTTAATATTTGTTATAGCAATTATTCTACTTACATCTGTA
    ATAGGAATTGTTGGACGATACATGAGTCGTCAACGTCTATTAAAATCTATGGAAACATTA
    TGGCAAACGATTTCTCCATTAGAAGCTTTTATCAGACCGAACTCACATTTCGACTATGAG
    TATAAGCTCTACAAGGAAAAATTTGAATCACATTCATTAGTTGATGATAAAACTTGGTCC
    GACTTAAATATGAATGCAATTTTTCATAAGATGAATTATAATTTAACAGCTATTGGTGAA
    ATGAAGCTATATGCCTGTTTACGTGGAATGCTTTCAATTACGAACAAATCATTACTTAGT
    TTATTTAATGATAATGCTGAATTTAGAAAAAACGTAACATATCATTTAGCTTTGATTGGT
    AAAACTGTTTATCCAACATTTCCAGACCAAATCACACCGGTAAAACGTCAAAATATATTG
    TTTCTATGCCCGTTTTTACCAGTTATCTCATTTGCAGTTATATTTATTAATTCACAAGTT
    GGTATTTTATTATTTCTTATGAGTTGCCTATTTAATATCATTTTATCAGCAACTTTAAAG
    CGTACATATGAGGATGACTTAAAATCTATCTTTTATGCATCCAATGTTTTAAAACAAGGC
    TATACTATCTCAAAAATTAAACATGCTCCACAACCTGAAGTCAATTTTAAGCAATTTAGA
    ACAGCACGTCATTTAACGAGTGTTTTAGCTGAAGTTAATGATGAAGATATCGGAGCTATG
    GTAATTAAACTAGTTAAACTTATTTTCATGCTTGATTATGTTTTATTTCATTCAATTCAA
    AAAAGCTATACAACACATATGAATGAGCTTAAAAATTGTTTCGATTACATAGCTGAATTA
    GATAATCATTATGCATTAGCAATGTATCGTAGAACGCTAGAATGTTATACTGAACCACAA
    ATTGATGATACAAATGATGGCATAGTATTCTCTGAGTTAACACATCCACTCATAGCAGAT
    GCAGTAGCCAATGATTTCTCACTTTCACAAAATATACTGTTAACTGGGTCTAATGCTTCG
    GGTAAATCAACATTTATGAAATCCATAGCAATAAACATTATTCTTGCATCGGCTATACAA
    ACAGTTACCGCAAGCAAATTTGTATATCAACCTGGAATTGTGTTCACGTCAATGGCAAAT
    GCCGATGATGTGTTATCAGGCGATAGTTATTTTATGGCTGAATTAAAATCTATTAAGCGT
    ATTGTTGAAATTCCAGATAATCAAAAAATATACTGCTTTATCGATGAAATTTTTAAAGGT
    ACCAACACAACTGAACGAATTGCCGCTTCAGAATCAGTACTATCATTTTTACATGAAAAA
    TCTAACTTTAGAGTTATTGCAGCAACACATGATATTGAGTTAGCTGAACTCTTAAAACAA
    CGTTATGAAAATTATCATTTCAATGAGGTAATAGAAAATAATAACATACATTTTGATTAC
    AAAATTAAGCCTGGCAAAGCAAATACTCGTAATGCCATCGAATTATTAAAAATCACTTCA
    TTTCCAGCAAAAATATATGAACGAGCAAAAGATAATGTTTCCAATGGTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1611

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS10640 [old locus tag: SA1853 ]
  • symbol: SA_RS10640
  • description: DNA mismatch repair protein MutS
  • length: 536
  • theoretical pI: 7.40563
  • theoretical MW: 61255.4
  • GRAVY: 0.0115672

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA mismatch repair protein MutS (TIGR01070; HMM-score: 120.5)
    and 4 more
    Genetic information processing DNA metabolism Other MutS2 family protein (TIGR01069; HMM-score: 62.8)
    P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 13.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 12.7)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 11.8)
  • TheSEED: see SA1853
  • PFAM:
    P-loop_NTPase (CL0023) MutS_V; MutS domain V (PF00488; HMM-score: 104.2)
    and 10 more
    AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 20.4)
    AAA_14; AAA domain (PF13173; HMM-score: 19.9)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 19.4)
    G-alpha; G-protein alpha subunit (PF00503; HMM-score: 16.8)
    FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 15.2)
    ABC_tran; ABC transporter (PF00005; HMM-score: 14.2)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 13.2)
    AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 12.2)
    no clan defined Baculo_11_kDa; Baculovirus 11 kDa family (PF06143; HMM-score: 7.1)
    Sigma_reg_N; Sigma factor regulator N-terminal (PF13800; HMM-score: 6.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.07
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.18
    • Extracellular Score: 0.21
    • Internal Helices: 3
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.087395
    • TAT(Tat/SPI): 0.001793
    • LIPO(Sec/SPII): 0.025101
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSTNQTFLIFVIAIILLTSVIGIVGRYMSRQRLLKSMETLWQTISPLEAFIRPNSHFDYEYKLYKEKFESHSLVDDKTWSDLNMNAIFHKMNYNLTAIGEMKLYACLRGMLSITNKSLLSLFNDNAEFRKNVTYHLALIGKTVYPTFPDQITPVKRQNILFLCPFLPVISFAVIFINSQVGILLFLMSCLFNIILSATLKRTYEDDLKSIFYASNVLKQGYTISKIKHAPQPEVNFKQFRTARHLTSVLAEVNDEDIGAMVIKLVKLIFMLDYVLFHSIQKSYTTHMNELKNCFDYIAELDNHYALAMYRRTLECYTEPQIDDTNDGIVFSELTHPLIADAVANDFSLSQNILLTGSNASGKSTFMKSIAINIILASAIQTVTASKFVYQPGIVFTSMANADDVLSGDSYFMAELKSIKRIVEIPDNQKIYCFIDEIFKGTNTTERIAASESVLSFLHEKSNFRVIAATHDIELAELLKQRYENYHFNEVIENNNIHFDYKIKPGKANTRNAIELLKITSFPAKIYERAKDNVSNG

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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