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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS10520 [old locus tag: SA1833 ]
  • pan locus tag?: SAUPAN005253000
  • symbol: SA_RS10520
  • pan gene symbol?:
  • synonym:
  • product: transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS10520 [old locus tag: SA1833 ]
  • symbol: SA_RS10520
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 2070021..2070239
  • length: 219
  • essential: no DEG

Accession numbers[edit | edit source]

  • Location: NC_002745 (2070021..2070239) NCBI
  • BioCyc: SA_RS10520 BioCyc
  • MicrobesOnline: see SA1833

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGACTATTTTAGCGAATACTAGAAAGTTTAAAGAAGCCATGTTCTTAAAAGGCTTTAAT
    TTATCTGATTTATCACGTGAAACAGGTGTTGGAATTTCTTATTTAAGCCAAATTATTAAT
    GGTAAAAAGATTCCAAGCCCTAAATTAGCTAAGAAAATGGCAGAAGTTTTACAAGTTGAG
    GTAAATGAATTATTTGAATTTGAAGTAAAGGAGGCATAA
    60
    120
    180
    219

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS10520 [old locus tag: SA1833 ]
  • symbol: SA_RS10520
  • description: transcriptional regulator
  • length: 72
  • theoretical pI: 9.75783
  • theoretical MW: 8120.51
  • GRAVY: -0.0861111

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage-associated protein, BcepMu gp16 family (TIGR04111; HMM-score: 14.8)
    Genetic information processing Mobile and extrachromosomal element functions Other addiction module antidote protein, HigA family (TIGR02607; HMM-score: 14.3)
    Signal transduction Regulatory functions DNA interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 14.3)
    Signal transduction Regulatory functions Protein interactions addiction module antidote protein, HigA family (TIGR02607; HMM-score: 14.3)
    Cellular processes Cellular processes Detoxification cyanase (TIGR00673; EC 4.2.1.104; HMM-score: 13.2)
    Hypothetical proteins Conserved TIGR02147 family protein (TIGR02147; HMM-score: 12.8)
  • TheSEED: see SA1833
  • PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 46.5)
    and 4 more
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 36.5)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 25.8)
    HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 24.3)
    HTH_35; Winged helix-turn-helix DNA-binding (PF13693; HMM-score: 17.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002044
    • TAT(Tat/SPI): 0.000725
    • LIPO(Sec/SPII): 0.000339
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]