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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS06390 [old locus tag: SA1130 ]
  • pan locus tag?: SAUPAN003591000
  • symbol: SA_RS06390
  • pan gene symbol?:
  • synonym:
  • product: metallophosphoesterase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS06390 [old locus tag: SA1130 ]
  • symbol: SA_RS06390
  • product: metallophosphoesterase
  • replicon: chromosome
  • strand: +
  • coordinates: 1284212..1285009
  • length: 798
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (1284212..1285009) NCBI
  • BioCyc: SA_RS06390 BioCyc
  • MicrobesOnline: see SA1130

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAGAATAATGTTTATAGGGGATATCGTAGGTAAAATTGGACGAGACGCAATTGAAACG
    TACATACCTCAACTGAAGCAAAAGTATAAACCAACAGTTACAATTGTAAATGCTGAAAAT
    GCAGCACATGGTAAAGGTTTGACTGAAAAAATATATAAACAATTACTAAGAAATGGTGTA
    GATTTCATGACTATGGGTAATCACACATATGGTCAACGTGAAATTTATGATTTTATAGAT
    GAAGCAAAACGACTAGTAAGACCAGCGAATTTTCCGGATGAAGCGCCGGGAATTGGTATG
    AGATTTATACAAATTAATGATATTAAACTTGCAGTTATTAATCTGCAAGGAAGAGCGTTT
    ATGCCAGATATTGATGATCCTTTTAAAAAGGCAGATCAATTAGTCAAGGAAGCACAAGAA
    CAAACTCCGTTTATATTTGTTGATTTTCATGCAGAAACAACTTCTGAAAAGTATGCAATG
    GGATGGCATTTAGATGGTAGAGCTAGCGCTGTTGTTGGAACGCATACACACATTCAAACA
    GCAGATGAACGTATTTTACCAAAGGGGACAGGGTATATAACGGATGTTGGTATGACAGGT
    TTTTATGACGGCATTTTAGGAATAAATAAAACAGAGGTAATTGAGCGTTTTATCACTAGT
    TTGCCACAAAGACATGTTGTTCCAAATGAAGGTAGAAGTGTATTATCTGGTGTTGTTATT
    GATTTAGACAAAGAAGGTAAAACAAAGCACATCGAACGTATATTGATAAATGATGACCAT
    CCATTTTCAACATTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    798

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS06390 [old locus tag: SA1130 ]
  • symbol: SA_RS06390
  • description: metallophosphoesterase
  • length: 265
  • theoretical pI: 6.61158
  • theoretical MW: 29875
  • GRAVY: -0.308302

Function[edit | edit source]

  • TIGRFAM:
    Unknown function Enzymes of unknown specificity metallophosphoesterase, MG_246/BB_0505 family (TIGR00282; HMM-score: 351.5)
  • TheSEED: see SA1130
  • PFAM:
    Calcineurin (CL0163) YmdB; YmdB-like protein (PF13277; HMM-score: 359.2)
    and 1 more
    Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 32.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010764
    • TAT(Tat/SPI): 0.00021
    • LIPO(Sec/SPII): 0.00217
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRIMFIGDIVGKIGRDAIETYIPQLKQKYKPTVTIVNAENAAHGKGLTEKIYKQLLRNGVDFMTMGNHTYGQREIYDFIDEAKRLVRPANFPDEAPGIGMRFIQINDIKLAVINLQGRAFMPDIDDPFKKADQLVKEAQEQTPFIFVDFHAETTSEKYAMGWHLDGRASAVVGTHTHIQTADERILPKGTGYITDVGMTGFYDGILGINKTEVIERFITSLPQRHVVPNEGRSVLSGVVIDLDKEGKTKHIERILINDDHPFSTF

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]