SAUSA300 RS10120

PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_RS10120 [old locus tag: SAUSA300_1852 ]
• pan locus tag^?: SAUPAN004854000
• symbol: SAUSA300_RS10120
• pan gene symbol^?: —
• synonym:
• product: teichoic acid ABC transporter ATP-binding protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_RS10120 [old locus tag: SAUSA300_1852 ]
• symbol: SAUSA300_RS10120
• product: teichoic acid ABC transporter ATP-binding protein
• replicon: chromosome
• strand: -
• coordinates: 2014509..2016026
• length: 1518
• essential: unknown other strains

⊟Accession numbers

• Location: NC_007793 (2014509..2016026) NCBI
• BioCyc: see SAUSA300_1852
• MicrobesOnline: see SAUSA300_1852

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

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  ATGGGAAGTTCAATTGTTTTAAAGTTACTAAAAGTAACACACTACTATAGGAATAAACAG
  AATAAGAAATGGTATTTACCTTTTGGATATGATGCTGAAGATATCGATTTAAACAATATT
  AGTTTACATATTTATCAAGGAGAAGCATTAGGTATAATTGGTGAACCTGAATCTTCCAAA
  GCGTTGGTAGGTCAATTGTTGGCAGGTGCAATTAAACCTGATAAAGGTAAAGTAGTTTGT
  ACTGAAGATTTGTTCTACGGATATATTGAAGATCAATCGTTAATTCATCAAACTGTTGAA
  GCTTATACAGCGCAGTTAGTTCAACTATTTCCATATGAAATTAATGATCATAAAGCTGAA
  CAGATTATTCAATATGCACATTTAGGTGATTATAAAACGAAGCCGGTTAACCATATTTCG
  AAAGCGGCATACGCTCAATTACTATTAAGTATTGCACGCTCATCAAAATCAAATATTATT
  ATTTTAAATCATGTTATTGACTATTTAACACCACAATTTATGGAACGTGCGATTGAATTA
  ACAAATGATTATATTGAAAATAATTTAACGATTGTGTCAATTGGTGATGATATTGATAAA
  ATTTCACAAGTGAGTAACTACATAGCTTGGTTTTCACATGGTCAATTAAGAATGGAAGGG
  TCACTTAAACAAGTTATTCCATCTTTTAAAGAACATGAACGTGATCGATTAAGTCTAAAC
  TCAAAAGAAGAAATTGAAAACTTTGATTTAGATTGGAAAAAGAATCGTACAAGAATACCA
  GAGATGACCTATAATTTCAAACGTGTTGAGCGCTATAATCATGCAAAACCGCCTAAGTTT
  TTAGTGCGTTTTTGGACTTTGGCCTCAGGTACTATTTTAGGCTTAGCATTGATGATGTTG
  CTCATTTTCAATAATATAGGAATTATTTCGATAACAGATTTTACGAATCGTGCTACGATG
  CAAAATGAAAATAAAGATCCATATGGCGAAAAGTTAGCTTATGGAATTGCTTTTAATGGC
  AGTGTGGATATGCAAGGGGATAAACAAGTCACAATTCCAAAATATAGTGTAGTTACAATT
  ACTGGCGAAAATAGTAAAAATTATCGTGTTACCGCCGATAATAAGACTTACTATGTTAGT
  AAAGATAAATTAGAATATTTTAACCCGGCAGGTTTATATCAAACGCATAGTTTTAAAAAA
  TTAGCACCATATATGAAATCAAATTATAGTAATTACTATGCATACTTTAATAGTCAATTA
  CATAAAAAGCATAGTTCAGTTATAAAAACTTTAGTTCCTGATGATGATAACCGTTTCGTT
  GCATCCGTTACACAACAACCGATACAATTACTTTTCAATGATAATAATCAGTTATACGGT
  TTTGTTTATCCAATTGTAGATAAAAAAGAATTAAAAGATAAGTTTAATATTAACAATAAC
  ATTTGGATTACTAAAGTTGGGAATGGATATTGTATTGCCAATTTGAAAGAAGACAAATGG
  ATTTATATTGAATTGTAG
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⊟Protein

⊟General

• locus tag: SAUSA300_RS10120 [old locus tag: SAUSA300_1852 ]
• symbol: SAUSA300_RS10120
• description: teichoic acid ABC transporter ATP-binding protein
• length: 505
• theoretical pI: 8.41277
• theoretical MW: 58254
• GRAVY: -0.39604

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 43.2)
  Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 41)
  and 43 more
  lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 32.9)
  Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 30.7)
  Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 29.1)
  Metabolism Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 26)
  Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 25.5)
  Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 24.1)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 24.1)
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 23.5)
  Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 23.5)
  Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 23.2)
  Metabolism Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 22.8)
  Metabolism Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 22.7)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 22.3)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 20.7)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 20.3)
  2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 20.2)
  D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 19)
  Metabolism Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 18.9)
  Metabolism Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 18.9)
  ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 18.1)
  Cellular processes Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 17.7)
  Metabolism Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 17.7)
  thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 17.3)
  Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 17.2)
  Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 17.2)
  Metabolism Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 16.6)
  ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 16.1)
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 15.5)
  Metabolism Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 15.5)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 15.2)
  Metabolism Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 14.6)
  Metabolism Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 14.5)
  Metabolism Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 14.3)
  Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 14.2)
  Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 14.2)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 13.6)
  Metabolism Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 13.6)
  gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 13.2)
  Cellular processes Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 13)
  Metabolism Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 13)
  thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 12.3)
  Cellular processes Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 12.2)
  proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 11.1)
• TheSEED: see SAUSA300_1852
• PFAM:
  P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 27.1)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helix: 1
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005976
  • TAT(Tat/SPI): 0.000099
  • LIPO(Sec/SPII): 0.00046
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI: 446457980 NCBI
• RefSeq: WP_000535834 NCBI
• UniProt: see SAUSA300_1852

⊟Protein sequence

• MGSSIVLKLLKVTHYYRNKQNKKWYLPFGYDAEDIDLNNISLHIYQGEALGIIGEPESSKALVGQLLAGAIKPDKGKVVCTEDLFYGYIEDQSLIHQTVEAYTAQLVQLFPYEINDHKAEQIIQYAHLGDYKTKPVNHISKAAYAQLLLSIARSSKSNIIILNHVIDYLTPQFMERAIELTNDYIENNLTIVSIGDDIDKISQVSNYIAWFSHGQLRMEGSLKQVIPSFKEHERDRLSLNSKEEIENFDLDWKKNRTRIPEMTYNFKRVERYNHAKPPKFLVRFWTLASGTILGLALMMLLIFNNIGIISITDFTNRATMQNENKDPYGEKLAYGIAFNGSVDMQGDKQVTIPKYSVVTITGENSKNYRVTADNKTYYVSKDKLEYFNPAGLYQTHSFKKLAPYMKSNYSNYYAYFNSQLHKKHSSVIKTLVPDDDNRFVASVTQQPIQLLFNDNNQLYGFVYPIVDKKELKDKFNINNNIWITKVGNGYCIANLKEDKWIYIEL

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications