NCBI: 03-AUG-2016
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus NCTC8325
- locus tag: SAOUHSC_02818
- pan locus tag?: SAUPAN006148000
- symbol: SAOUHSC_02818
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAOUHSC_02818
- symbol: SAOUHSC_02818
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 2596034..2597197
- length: 1164
- essential: no DEG
⊟Accession numbers[edit | edit source]
- Gene ID: 3921257 NCBI
- RefSeq: YP_501276 NCBI
- BioCyc: G1I0R-2654 BioCyc
- MicrobesOnline: 1291247 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1141ATGATTAATAGTAATATCAGATTATATATTCTAGGATTTTTAGCATTTTTCGCATCATTG
ATTCAAAACATATACACGCCTATTATTCCGAGACTATATGACGATTTTCAAGTACCACTA
TTTTGGATAAATGCGACAGTTGGCGGTTTTATATTTATCGTTGCAGTTATGCAAATTGTA
CTTGGTAGAAGTATAGATTCTCGTGATTCGAAAAAAGTACTTTTAACGGGATTGGGAATA
GTAATCATATCTAGCTTTATTTGTGCAGTGACACATAACTTTATATTATTTGCTATATCA
AGGTTATTTCAAGCAATTGGTTGCGGAATTATTCCTCTCGTGACTTTAACTTTATTAGCC
AAACTAAGTACAGATAATGGTAGAGCTCAAGCTATGGCGAACTATCAAATATTTTTATCA
TGTGCACCAGCTTTGGCACCAATCTTAGGGAGTACTTTAGGTGCAAGATGGGATTATATT
GGTATTTTTAGTTTTTTGCTCGTTATATCTATCGTATTATTTTTGATTATCTTTTTTATT
GATATTCCAAATGTTGAAAAAGGGATTGTAAAATTAACTGAAAAAATTGAAGAAAAATAT
TTGACCGATAAAGTGTTTATTACTTTAGTGACATTGGGATTTTTAATATTTTTTACGTAC
TTTTCAATATTAGTTTATTTACCAACATTATTAAATAATACCTATGATATAGGCGTTGGA
ATATCAGGAGTTTTGTTTTTACCTATTACTGTTAGTGTTATATTAGGAAGTTTATTTTAT
AAGCGATTTTCAAAAAAATATAATGAAATAATGATACTTCGTGTTACTATAACTGGATTT
GCTATATTTACGTTATTGTTTGGATGGTTAAACGAATCAAATGTAATTATATTATCAGTA
ATTATATTTATATTAGGTACTTGTGTTGGTATTGTGCCAGCTTTGCTGTCTACTATAATT
TCTAAAAGGTTTGAACATATAAAAGGGAAAGTGCTAGGTGTATTTAATTTTGTGAGATAT
ATTGGAATGACTGTCGGTGCATTATTAATTGGTATCATTTCTCAGCCGTTGGTAGCCTTT
TACTTCACAACTATAACTATCATGTTAATAGTAATATTTCTTTATATAAAGATAGTTGAC
TTTCAGCTAAAGTATGCCAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAOUHSC_02818
- symbol: SAOUHSC_02818
- description: hypothetical protein
- length: 387
- theoretical pI: 9.77147
- theoretical MW: 43229.9
- GRAVY: 1.11705
⊟Function[edit | edit source]
- TIGRFAM: drug resistance transporter, Bcr/CflA subfamily (TIGR00710; HMM-score: 101.2)and 4 moremultidrug resistance protein (TIGR00880; HMM-score: 70.1)Cellular processes Toxin production and resistance drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 55.6)Transport and binding proteins Other drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 55.6)Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, aromatic acid:H+ symporter (AAHS) family (TIGR00895; HMM-score: 28.7)
- TheSEED :
- Major facilitator family transporter
- PFAM: MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 147.8)and 3 moreMFS_3; Transmembrane secretion effector (PF05977; HMM-score: 20.3)MFS_2; MFS/sugar transport protein (PF13347; HMM-score: 7)no clan defined DUF4220; Domain of unknown function (DUF4220) (PF13968; HMM-score: 5.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 12
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0.17
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.027152
- TAT(Tat/SPI): 0.000354
- LIPO(Sec/SPII): 0.064259
- predicted transmembrane helices (TMHMM): 12
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MINSNIRLYILGFLAFFASLIQNIYTPIIPRLYDDFQVPLFWINATVGGFIFIVAVMQIVLGRSIDSRDSKKVLLTGLGIVIISSFICAVTHNFILFAISRLFQAIGCGIIPLVTLTLLAKLSTDNGRAQAMANYQIFLSCAPALAPILGSTLGARWDYIGIFSFLLVISIVLFLIIFFIDIPNVEKGIVKLTEKIEEKYLTDKVFITLVTLGFLIFFTYFSILVYLPTLLNNTYDIGVGISGVLFLPITVSVILGSLFYKRFSKKYNEIMILRVTITGFAIFTLLFGWLNESNVIILSVIIFILGTCVGIVPALLSTIISKRFEHIKGKVLGVFNFVRYIGMTVGALLIGIISQPLVAFYFTTITIMLIVIFLYIKIVDFQLKYAK
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: [1]
Multi-gene expression profiles
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
PLoS Genet: 2016, 12(4);e1005962
[PubMed:27035918] [WorldCat.org] [DOI] (I e)