NCBI date : _
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus NCTC8325
- locus tag: SAOUHSC_02553
- pan locus tag?: SAUPAN005745000
- symbol: SAOUHSC_02553
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAOUHSC_02553
- symbol: SAOUHSC_02553
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 2347253..2348194
- length: 942
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
- Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901GTGACTAAGAAAGTTTATTTTAACCACGATGGTGGTGTAGATGATTTAGTATCTCTATTT
TTATTATTACAAATGGAAAACGTTCAATTGATAGGGGTCAGTACAATTGGTGCTGATTGT
TATTTAGAGCCATCTTTGAGCGCATCAGTAAAAATTATTAATCGTTTTTCAAATGAAGAT
ATTCAAGTTGCGCCATCATATGAACGAGGAAAAAATCCATTTCCTAAAGAATGGCGTATG
CATGCCTTTTTTATGGACGCATTGCCAATTTTAAATGAGCCAGTCAAACATGTTGCTTCA
AATGTGAGCGACAAAGAAGCCTTTGAAGACATTATTCAAACTTTAAAGAGACAATCAGAA
AAAGTAACATTATTATTTACAGGCCCGCTTACAGATTTAGCAAAAGCACTACAAAAAGAT
TCATCTATCGTTCAGTATATAGAAAAATTAGTTTGGATGGGTGGCACCTTTTTACCAAAA
GGAAATGTTGAAGAACCTGAGCATGATGGTTCTGCAGAATGGAATGCATATTGGGATCCA
GAAGCGGTTAAAATTGTTTTTGATAGCGATATAGAGATTGATATGGTTGCTTTAGAAAGT
ACGAATCAAGTACCGCTAACGTTAGATGTTAGACAAAGATGGGCGAATGAACGCCAATAT
ACGGGCATTGATTTTTTAGGAGTAAGTTATGCAGCGGTACCACCATTAACACACTTTATA
ACAAATTCTACTTACTTTTTATGGGATGTTTTAACGACTGCTTATATTGGTAACAAGGAC
TTGGTTCATTCAATTGAGAAAAAAGTCGATGTAATAAGTTATGGACCAAGTCAAGGTAAG
ACATTTGAGTGTAAAGATGGGCGCAAAATTAATGTCATAAATCATGTAGATAACAACGCA
TTTTTTGATTATATAACTGCACTTGCTAAAAAAGTAAATTAA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
942
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAOUHSC_02553
- symbol: SAOUHSC_02553
- description: hypothetical protein
- length: 313
- theoretical pI: 4.78529
- theoretical MW: 35361.9
- GRAVY: -0.19393
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone O-succinylbenzoate-CoA ligase (TIGR01923; EC 6.2.1.26; HMM-score: 13.8)
- TheSEED :
- Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1)
Nucleosides and Nucleotides Purines Purine conversions Inosine-uridine preferring nucleoside hydrolase (EC 3.2.2.1)and 1 more - PFAM: no clan defined IU_nuc_hydro; Inosine-uridine preferring nucleoside hydrolase (PF01156; HMM-score: 172.6)
⊟Structure, modifications & interactions[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
- interaction partners:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.066744
- TAT(Tat/SPI): 0.002157
- LIPO(Sec/SPII): 0.005834
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTKKVYFNHDGGVDDLVSLFLLLQMENVQLIGVSTIGADCYLEPSLSASVKIINRFSNEDIQVAPSYERGKNPFPKEWRMHAFFMDALPILNEPVKHVASNVSDKEAFEDIIQTLKRQSEKVTLLFTGPLTDLAKALQKDSSIVQYIEKLVWMGGTFLPKGNVEEPEHDGSAEWNAYWDPEAVKIVFDSDIEIDMVALESTNQVPLTLDVRQRWANERQYTGIDFLGVSYAAVPPLTHFITNSTYFLWDVLTTAYIGNKDLVHSIEKKVDVISYGPSQGKTFECKDGRKINVINHVDNNAFFDYITALAKKVN
⊟Peptides[edit | edit source]
- experimentally validated: PeptideAtlas [1] [2]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- sigma factors : _
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: [3]
Multi-gene expression profiles
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Maren Depke, Stephan Michalik, Alexander Rabe, Kristin Surmann, Lars Brinkmann, Nico Jehmlich, Jörg Bernhardt, Michael Hecker, Bernd Wollscheid, Zhi Sun, Robert L Moritz, Uwe Völker, Frank Schmidt
A peptide resource for the analysis of Staphylococcus aureus in host-pathogen interaction studies.
Proteomics: 2015, 15(21);3648-61
[PubMed:26224020] [WorldCat.org] [DOI] (I p) - ↑ Stephan Michalik, Maren Depke, Annette Murr, Manuela Gesell Salazar, Ulrike Kusebauch, Zhi Sun, Tanja C Meyer, Kristin Surmann, Henrike Pförtner, Petra Hildebrandt, Stefan Weiss, Laura Marcela Palma Medina, Melanie Gutjahr, Elke Hammer, Dörte Becher, Thomas Pribyl, Sven Hammerschmidt, Eric W Deutsch, Samuel L Bader, Michael Hecker, Robert L Moritz, Ulrike Mäder, Uwe Völker, Frank Schmidt
A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions.
Sci Rep: 2017, 7(1);9718
[PubMed:28887440] [WorldCat.org] [DOI] (I e) - ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
PLoS Genet: 2016, 12(4);e1005962
[PubMed:27035918] [WorldCat.org] [DOI] (I e)