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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI date : _

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01911
  • pan locus tag?: SAUPAN004505000
  • symbol: SAOUHSC_01911
  • pan gene symbol?: tnp2
  • synonym:
  • product: IS200 family transposase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_01911
  • symbol: SAOUHSC_01911
  • product: IS200 family transposase
  • replicon: chromosome
  • strand: -
  • coordinates: 1820862..1821347
  • length: 486
  • essential: no [1] DEG

⊟Accession numbers[edit | edit source]

  • Gene ID: 3921053 NCBI
  • RefSeq: YP_500412 NCBI

⊟Phenotype[edit | edit source]

  • Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
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    481
    ATGTCATCTGACACAAACAGTTTAGCACATACAAAATGGAATTGTAAGTATCATATTGTC
    TTTGCACCTAAATACAGAAGACAAGTGATATATGGAAAAATAAAAAAAGATATAGGGATT
    ATATTGCGTCAATTATGTGAAAGAAAAGGTGTAGAGATAATTGAAGCAGAGGCATGTAAA
    GATCATATCCATATGTTAGTTAGTATACCACCCAAACTTGGGGTATCATCATTTGTTGGC
    TATTTAAAAGGAAAAAGTAGTTTAATGATATTTGATAGACATGCTAACTTAAAGTATAGA
    TATGGAAATAGAAAGTTTTGGTGTAAAGGATTTTATGTGGATACAGTAGGTAGAAATAAA
    AAAGTGATTGAAAATTATATTCGTAATCAATTACAAGAGGATATCGTTGCAGACCAAATC
    TCAATGGAAGAATATTTAGATCCTTTCACTGGAGAGAAAAATAAAAAAAGAAAGAAAAAA
    GAGTAA
    60
    120
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    240
    300
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    486

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAOUHSC_01911
  • symbol: SAOUHSC_01911
  • description: IS200 family transposase
  • length: 161
  • theoretical pI: 10.1718
  • theoretical MW: 18905.9
  • GRAVY: -0.599379

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01109138: hypothetical protein
  • PFAM:
    HUH (CL0481) Y1_Tnp; Transposase IS200 like (PF01797; HMM-score: 129.6)

⊟Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • interaction partners:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003054
    • TAT(Tat/SPI): 0.00031
    • LIPO(Sec/SPII): 0.001118
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI: 88195606 NCBI
  • UniProt: Q2G1W3 UniProt
  • protein Genbank : _
  • RefSeq: YP_500412 NCBI

⊟Protein sequence[edit | edit source]

  • MSSDTNSLAHTKWNCKYHIVFAPKYRRQVIYGKIKKDIGIILRQLCERKGVEIIEAEACKDHIHMLVSIPPKLGVSSFVGYLKGKSSLMIFDRHANLKYRYGNRKFWCKGFYVDTVGRNKKVIENYIRNQLQEDIVADQISMEEYLDPFTGEKNKKRKKKE

⊟Peptides[edit | edit source]

  • experimentally validated: data available for COL

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • sigma factors : _
  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Roy R Chaudhuri, Andrew G Allen, Paul J Owen, Gil Shalom, Karl Stone, Marcus Harrison, Timothy A Burgis, Michael Lockyer, Jorge Garcia-Lara, Simon J Foster, Stephen J Pleasance, Sarah E Peters, Duncan J Maskell, Ian G Charles
    Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH).
    BMC Genomics: 2009, 10;291
    [PubMed:19570206] [WorldCat.org] [DOI] (I e)
  2. ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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