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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS08505 [old locus tag: SACOL1667 ]
  • pan locus tag?: SAUPAN004208000
  • symbol: SACOL_RS08505
  • pan gene symbol?:
  • synonym:
  • product: collagenase-like protease

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS08505 [old locus tag: SACOL1667 ]
  • symbol: SACOL_RS08505
  • product: collagenase-like protease
  • replicon: chromosome
  • strand: -
  • coordinates: 1695012..1696280
  • length: 1269
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_002951 (1695012..1696280) NCBI
  • BioCyc: SACOL_RS08505 BioCyc
  • MicrobesOnline: see SACOL1667

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAAGACAATAGAAGAGATTAAATCAACTCCTAAAACAGTTATGAAGAAACCAGAATTA
    TTAGCACCTGCTGGAAACTTAGAAAAGTTAAAAATAGCAGTACATTATGGCGCTGATGCC
    GTATTTTTAGGTGGTCAAGAATATGGATTACGTTCAAATGCTGATAATTTCACGATGGAA
    GAAATAGCTGAAGGTGTTGAATTTGCGAACCGTTACGGTGCCAAAATTTATGTTACGACA
    AATATTATTGCACATGATGAGAATATTGAAGGTCTAGAATCATATTTGCGTAATTTGGAA
    AAGACTGGTGCGACAGGTATCATTGTTGCAGATCCTTTAATTATCGAAACATGTAAAGAA
    GTTGCGCCAAAACTTGAAATTCATTTATCTACTCAACAATCACTTTCTAATTACAAAGCT
    GTAGAATATTGGAAAGAAGAAGGATTGGATCGTGTTGTATTAGCACGTGAGACCGGCGCG
    ATGGAAATGCGTGAAATGAAGGAAAAAGTAGATATTGAAATCGAAGCATTTATTCATGGT
    GCTATGTGTATCGCCTATTCAGGTAGATGTACATTAAGTAATCATATGACTGCAAGGGAT
    TCCAACAGAGGCGGTTGCTGTCAAAGTTGCCGTTGGGATTATGAATTATTAGAAGTTGAT
    GATAATGGTGAACTTGATGTTTTTTATAATCAAGGTGAAGTTACACCGTTTGCGATGAGT
    CCTAAAGATTTAAAATTAATCGAATCAATTCCTCAAATGATGGATATTGGTGTGGACTCA
    TTAAAAATTGAAGGACGTATGAAGTCAATTCATTATATTGCAACAGTTGTCTCAGTATAT
    CGTAAAGTCATTGATGCGTATGCGGCAGATCCTGACAACTTTAAGATTAATCCGGAATGG
    TTAATAGAGTTAGATAAATGTGCAAATAGAGACACTGCACCAGCATTCTTTGAGGGAACA
    CCTGGTTATGAAGAACAGATGTTTGGTCAACAACAATCTAAAAAATCATCATTTGATTTT
    TGTGGTTTGGTATTAGACTATAATGAAGATACAAAAATTGCGACTATTCAACAACGAAAT
    AACTTTAAACCAGGTCAAGAAATAGAATTCTTTGGTCCAGAAATTGAAACATTTACACAA
    GTAGTAGAAGCAATTTATGATGAAGAAGGTAACAGCTTAGACGCGGCGCGCCATCCATTA
    CAAATCGTTCAAATTAAAGTGGATCGCCCGATATATCCAAACAACATGATGAGAAAGGAA
    ATTGGCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1269

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL_RS08505 [old locus tag: SACOL1667 ]
  • symbol: SACOL_RS08505
  • description: collagenase-like protease
  • length: 422
  • theoretical pI: 4.49587
  • theoretical MW: 47644.8
  • GRAVY: -0.379384

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SACOL1667
  • PFAM:
    no clan defined Peptidase_U32; Peptidase family U32 (PF01136; HMM-score: 286.7)
    and 3 more
    Peptidase_U32_C; Peptidase family U32 C-terminal domain (PF16325; HMM-score: 88.8)
    TIM_barrel (CL0036) Radical_SAM; Radical SAM superfamily (PF04055; HMM-score: 15.7)
    no clan defined PucR; Purine catabolism regulatory protein-like family (PF07905; HMM-score: 12.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005131
    • TAT(Tat/SPI): 0.000485
    • LIPO(Sec/SPII): 0.000603
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKTIEEIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLGGQEYGLRSNADNFTMEEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKTGATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGAMEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLEVDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATVVSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSKKSSFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNSLDAARHPLQIVQIKVDRPIYPNNMMRKEIG

Experimental data[edit | edit source]

  • experimentally validated: see SACOL1667
  • protein localization: see SACOL1667
  • quantitative data / protein copy number per cell: see SACOL1667
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]