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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS04300 [old locus tag: SACOL0835 ]
  • pan locus tag?: SAUPAN002699000
  • symbol: SACOL_RS04300
  • pan gene symbol?: —
  • synonym:
  • product: DUF4887 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS04300 [old locus tag: SACOL0835 ]
  • symbol: SACOL_RS04300
  • product: DUF4887 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 862387..863016
  • length: 630
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (862387..863016) NCBI
  • BioCyc: G1G4B-905 BioCyc
  • MicrobesOnline: see SACOL0835

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCGAATCAAAATTACGACTACAATAAAAATGAAGATGGAAGTAAGAAGAAAATGAGT
    ACAACAGCGAAAGTAGTTAGCATTGCGACGGTATTGCTATTACTCGGAGGATTAGTATTT
    GCAATTTTTGCATATGTAGATCATTCGAATAAAGCTAAAGAACGTATGTTGAACGAACAA
    AAGCAGGAACAAAAAGAAAAGCGTCAAAAAGAAAATGCAGAAAAAGAGAGAAAGAAAAAG
    CAACAAGAGGAAAAAGAGCAGAATGAGCTAGATTCACAAGCAAACCAATATCAGCAATTG
    CCACAGCAGAATCAATATCAATATGTGCCACCTCAGCAACAAGCACCTACAAAGCAACGT
    CCTGCTAAAGAAGAGAATGATGATAAAGCATCAAAGGATGAGTCGAAAGATAAGGATGAC
    AAAGCATCTCAAGATAAATCAGATGATAATCAGAAGAAAACTGATGATAATAAACAACCA
    GCTCAGCCTAAACCACAGCCGCAACAACCAACACCAAAGCCAAATAATAATCAACAAAAC
    AATCAATCAAATCAGCAAGCAAAACCACAAGCACCACAACAAAATAGCCAATCAACAACA
    AATAAACAAAATAATGCTAATGATAAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    630

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS04300 [old locus tag: SACOL0835 ]
  • symbol: SACOL_RS04300
  • description: DUF4887 domain-containing protein
  • length: 209
  • theoretical pI: 9.70055
  • theoretical MW: 24070
  • GRAVY: -1.97368

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Adaptations to atypical conditions phage shock protein C (TIGR02978; HMM-score: 11.5)
    and 1 more
    Genetic information processing DNA metabolism Other MutS2 family protein (TIGR01069; HMM-score: 3.5)
  • TheSEED: see SACOL0835
  • PFAM:
    no clan defined DUF4887; Domain of unknown function (DUF4887) (PF16228; HMM-score: 171.7)
    and 9 more
    DUF4199; Protein of unknown function (DUF4199) (PF13858; HMM-score: 20.7)
    DUF4574; Domain of unknown function (DUF4574) (PF15141; HMM-score: 18.6)
    Transporter (CL0375) Connexin; Connexin (PF00029; HMM-score: 15.2)
    no clan defined Neurensin; Neurensin (PF14927; HMM-score: 12.9)
    MaAIMP_sms; Putative methionine and alanine importer, small subunit (PF16951; HMM-score: 11.4)
    MFS (CL0015) TLC; TLC ATP/ADP transporter (PF03219; HMM-score: 9.8)
    GPCR_A (CL0192) 7tm_1; 7 transmembrane receptor (rhodopsin family) (PF00001; HMM-score: 6.9)
    Tetraspannin (CL0347) DUF4064; Protein of unknown function (DUF4064) (PF13273; HMM-score: 6.9)
    MFS (CL0015) Acatn; Acetyl-coenzyme A transporter 1 (PF13000; HMM-score: 6.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.105218
    • TAT(Tat/SPI): 0.000937
    • LIPO(Sec/SPII): 0.005709
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL0835
  • protein localization: see SACOL0835
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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