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Revision as of 13:44, 10 March 2016 by AureoSysAdmin (talk | contribs) (Text replacement - "gene Genbank" to "gene RefSeq")
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Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS06040 [old locus tag: NWMN_1069 ]
  • symbol: NWMN_RS06040
  • product: fibrinogen-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1172925..1173422
  • length: 498
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq: WP_000791587 NCBI

Phenotype[edit | edit source]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAAAAATAAATTGATAGCAAAATCTTTATTAACATTAGCGGCAATAGGTATTACTACA
    ACTACAATTGCGTCAACAGCAGATGCGAGCGAAGGATACGGTCCAAGAGAAAAGAAACCA
    GTGAGTATTAATCACAATATCGTAGAGTACAATGATGGTACTTTTAAATATCAATCTAGA
    CCAAAATTTAACTCAACACCTAAATATATTAAATTCAAACATGACTATAATATTTTAGAA
    TTTAACGATGGTACATTCGAATATGGTGCACGTCCACAATTTAATAAACCAGCAGCGAAA
    ACTGATGCAACTATTAAAAAAGAACAAAAATTGATTCAAGCTCAAAATCTTGTGAGAGAA
    TTTGAAAAAACACATACTGTCAGTGCACACAGAAAAGCACAAAAGGCAGTCAACTTAGTT
    TCGTTTGAATACAAAGTGAAGAAAATGGTCTTACAAGAGCGAATTGATAATGTATTAAAA
    CAAGGATTAGTTAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    498

Protein[edit | edit source]

Protein Data Bank: 1EFB
Protein Data Bank: 3D5R
Protein Data Bank: 3D5S

General[edit | edit source]

  • locus tag: NWMN_RS06040 [old locus tag: NWMN_1069 ]
  • symbol: NWMN_RS06040
  • description: fibrinogen-binding protein
  • length: 165
  • theoretical pI: 10.4514
  • theoretical MW: 18764.5
  • GRAVY: -0.632121

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined efb-c; Extracellular fibrinogen binding protein C terminal (PF12199; HMM-score: 130.8)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • interaction partners:

Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.02
    • Extracellular Score: 9.98
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 29 aa
    • SP(Sec/SPI): 0.991978
    • TAT(Tat/SPI): 0.003351
    • LIPO(Sec/SPII): 0.004114
    • Cleavage Site: CS pos: 29-30. ADA-SE. Pr: 0.9025
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI: 446714256 NCBI
  • UniProt: see NWMN_1069
  • protein Genbank : _
  • RefSeq: WP_000791587 NCBI

Protein sequence[edit | edit source]

  • MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK

Peptides[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • sigma factors : _
  • regulator: SaeR see NWMN_1069

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]